منابع مشابه
Drug Hypersensitivity
The in vitro diagnosis of allergic reactions to drugs is of particular interest to clinicians, as neither the clinical history nor the in vivo tests are fully conclusive. In addition, these tests may often be associated with risk, as occurs with the drug provocation test. Various different in vitro tests are available for the evaluation of drug hypersensitivity depending on the immunological me...
متن کاملPharmacogenetics of drug hypersensitivity.
Drug hypersensitivity reactions and severe cutaneous adverse drug reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis, are examples of serious adverse drug reactions mediated through a combination of metabolic and immunological mechanisms that could traditionally not have been predicted based on the pharmacological characteristics of the drug alone. The discovery of new a...
متن کاملDrug hypersensitivity: questionnaire
Drug hypersensitivity is a common and complicated problem in clinical practice. The clinical picture of drug hypersensitivity is very heterogeneous, encompassing such distinct diseases as morbilliform or bullous exanthema, urticaria, anaphylaxis, blood cell dyscrasia, fever, interstitial lung disease, hepatitis, nephritis, and various forms of autoimmune diseases. Drug hypersensitivity has take...
متن کاملMultiple Drug Hypersensitivity.
Multiple drug hypersensitivity (MDH) is a syndrome that develops as a consequence of massive T-cell stimulations and is characterized by long-lasting drug hypersensitivity reactions (DHR) to different drugs. The initial symptoms are mostly severe exanthems or drug rash with eosinophilia and systemic symptoms (DRESS). Subsequent symptoms due to another drug often appear in the following weeks, o...
متن کاملDrug hypersensitivity in Phramongkutklao Hospital.
OBJECTIVE To evaluate the prevalence of drug hypersensitivity, clinical manifestations, type of drugs involved, severity, and patients demographic data. STUDY DESIGN A cross-sectional descriptive study. MATERIAL AND METHOD The study was performed from January 1st, 2008 to December 31th, 2008 at Phramongkutklao Hospital. Data were collected from Pharmaceutical Department, Dermatology Unit, D...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2008
ISSN: 0306-5251,1365-2125
DOI: 10.1111/j.1365-2125.2007.03049.x